A novel highly efficient gene edting technique is described by Chiang et al., in Scientific Reports. This method combines an All-In-One Cas9D10A nickase vector with FACS enrichment, high-throughput genotypic and phenotypic clonal screening strategies to generate isogenic knockouts and knock-ins highly efficiently, with minimal off-target effects.
Read MoreSteve has been awarded this prestigious prize for "his outstanding contribution to defining the link between the basic mechanism of genomic DNA instability and its relationship to cancer.
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