To cope with the threat of genome instability, cells have evolved an intricate network of mechanisms ranging from cell cycle checkpoints to specialized DNA repair pathways known as the DNA damage response. These mechanisms are evolutionary conserved from prokaryotes to metazoans. However, in this EMBO Workshop of evolution, tissue- and species-specific divergence has contributed to development of additional layers of complexity. This workshop will cover the different aspects of the DNA damage response ranging from the evolutionary to the tissue- and organ-specific diversity aspects of the process And its impact on human health and disease.

Abstract submission deadline: 9th October 2026