Herzog M, Puddu F, Coates J, Geisler NJ, Forment JV, Jackson SP. (2018)
Scientific Reports [Epub ahead of print]
Genetic and chemo-genetic interactions have played key roles in elucidating the molecular mechanisms by which certain chemicals perturb cellular functions. Many studies have employed gene knockout collections or gene disruption/depletion strategies to identify routes for evolving resistance to chemical agents.